Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ InSolution™ Y-27632, Sterile-Filtered, Cell Culture-Tested
A 10 mM (2 mg/591 μL) sterile-filtered solution of Y-27632 in H2O.
MilliporeSigma™ Calbiochem™ InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2
The InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 controls the biological activity of Akt.
MilliporeSigma™ Calbiochem™ AY 9944
A cell-permeable amphiphilic diamine that blocks cholesterol biosynthesis and its esterification.
MilliporeSigma™ Calbiochem™ GSK-3 Inhibitor XVI
GSK-3 Inhibitor XVI - CAS 252917-06-9, is a cell-permeable, potent, ATP-competitive, and highly selective GSK-3 inhibitor (IC50 = 10 and 6.7 nM against GSK-3α and GSK-3β, respectively).
MilliporeSigma™ Calbiochem™ MPS1 Inhibitor, NMS-P715
The MPS1 Inhibitor, NMS-P715 controls the biological activity of MPS1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Pepstatin A, Synthetic
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
MilliporeSigma™ Calbiochem™ MMP-13 Substrate, Fluorogenic
A quenched fluorescence substrate for MMP-13 (collagenase-3; kcat/Km = 1.09 x 106 M-1 s-1).
MilliporeSigma™ Calbiochem™ 11beta-HSD1 Inhibitor, 10j
The 11beta-HSD1 Inhibitor, 10j, also referenced under CAS 1009373-58-3, controls the biological activity of 11beta-HSD1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Picrotoxin, Anamirta cocculin
A potent antagonist of GABA receptors (IC50 = 240 nM) at synapses in the central nervous system.
MilliporeSigma™ Calbiochem™ EGFR Inhibitor
The EGFR Inhibitor, also referenced under CAS 879127-07-8, controls the biological activity of EGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ RuBi-Nicotine
A highly water soluble Ruthenium-bisbipyridine-caged nicotine that can be un-caged by blue and green light
MilliporeSigma™ Calbiochem™ ISR Inhibitor, ISRIB
The cell-permeable, selective inhibitor of eIF2α/eIF2S1 Ser51 phosphorylation-initiated UPR response (≈25 to 200 nM) upon ER stress induction.
MilliporeSigma™ Calbiochem™ VEGFR Tyrosine Kinase Inhibitor II
The VEGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 269390-69-4, controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ I-BET
A 50 mM sterile-filtered solution of I-BET in DMSO.
MilliporeSigma™ Calbiochem™ Ezh2 Inhibitor III, SAH-EZH2
A helical 27-mer peptide with E54Q modification that directly binds to EDD (Kd = 320 nM) and disrupts protein-protein interaction of EED with EZH2 and EZH1.